Using X-ray technology to improve cancer treatment monitoring
Official title: Quantitative in vivo dosimetry for radiotherapy using model-based X-ray-induced acoustic computed tomography
Funded at University of California-Irvine · NIH-10978946 · Data updated 2026-11-12
This study is testing a new way to keep track of how much radiation is being delivered during cancer treatment using special X-rays that create sound waves, helping doctors see how well the treatment is working without changing the way they currently do things.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | September 3, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $80,229 |
| NIH project number | 1R50CA283816-01A1 |
| Project ID | NIH-10978946 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing radiotherapy for cancer who require precise monitoring of radiation dose delivery.
✕Less likely to help
Patients who are not receiving radiotherapy or those with conditions that do not involve radiation treatment may not benefit from this research.
What this research studies
This research focuses on developing a new method to monitor the delivery of radiation doses during cancer treatment using X-ray-induced acoustic computed tomography (XACT). By utilizing pulsed X-ray radiation, the project aims to detect acoustic waves generated by tissues as they absorb radiation. These waves will be analyzed to create detailed maps of radiation energy deposition, allowing for real-time monitoring of treatment effectiveness. The approach seeks to integrate easily into existing radiotherapy setups without disrupting current practices.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and effective cancer treatments by ensuring that radiation doses are delivered precisely to tumor sites.
How similar studies have gone: While XACT has been utilized in dosimetry research, this specific application for real-time monitoring in clinical settings is relatively novel.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Pandey, Prabodh Kumar — University of California-Irvine
- Study coordinator: Pandey, Prabodh Kumar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.