Using wearable technology to monitor emotional responses in patients with frontotemporal dementia

Digital monitoring of autonomic activity to detect empathy loss in behavioral variant frontotemporal dementia

['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-10895560

This study is looking at how changes in your body's automatic responses can help us understand why some people with behavioral variant frontotemporal dementia have trouble feeling empathy, using smartwatches to track these responses in a comfortable way.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10895560 on ClinicalTrials.gov

What this research studies

This research investigates how changes in autonomic nervous system activity can help understand the loss of empathy in patients with behavioral variant frontotemporal dementia (bvFTD). By utilizing advanced wearable technology, such as smartwatches, researchers aim to measure physiological responses unobtrusively, allowing for a more accurate assessment of empathy loss. The study seeks to identify specific patterns of autonomic activity that correlate with social and emotional dysfunction in these patients. This innovative approach aims to overcome limitations of traditional measurement methods that can restrict patient movement and introduce bias.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with behavioral variant frontotemporal dementia who are experiencing symptoms of social and emotional dysfunction.

Not a fit: Patients with other forms of dementia or those without significant social and emotional dysfunction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of empathy loss in bvFTD, potentially improving patient care and caregiver support.

How similar studies have performed: While the use of wearable technology in monitoring autonomic activity is gaining traction, this specific application in bvFTD is relatively novel and has not been extensively tested.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.