Using wearable sensors to monitor symptoms in myasthenia gravis patients
Official title: Wearable Sensor and Digital Technologies for Quantitative Assessment and Remote Monitoring of Symptoms in Myasthenia Gravis
Funded at Biosensics, LLC · NIH-10710321 · Data updated 2026-11-12
This study is creating a handy wearable device and a mobile app to help people with myasthenia gravis keep track of their symptoms every day, making it easier for them and their doctors to understand how they're doing without needing to go to the clinic all the time.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | September 15, 2022 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $973,917 |
| NIH project number | 4R44NS122672-02 |
| Project ID | NIH-10710321 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with myasthenia gravis who experience fluctuating muscle weakness and related symptoms.
✕Less likely to help
Patients who do not have myasthenia gravis or those with stable, non-fluctuating symptoms may not benefit from this research.
What this research studies
This research focuses on developing a wearable sensor and a mobile application to continuously monitor symptoms in patients with myasthenia gravis (MG), a chronic autoimmune disease that causes muscle weakness. The wearable device will track motor symptoms and functions, while the mobile app will assess speech and facial characteristics, providing a more comprehensive view of the patient's condition. This approach aims to replace traditional in-clinic assessments, which can be time-consuming and subjective, with real-time data collection that reflects the patient's daily experiences. By collaborating with Massachusetts General Hospital, the project seeks to enhance the understanding of MG and improve patient care.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely assessments of myasthenia gravis symptoms, ultimately improving patient management and treatment outcomes.
How similar studies have gone: Previous research has shown promise in using wearable technology for monitoring chronic conditions, indicating that this approach could be effective for myasthenia gravis as well.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
Related research
Other NIH-funded projects on the same topics.
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Understanding how autoimmunity causes myasthenia gravis
This project looks at why the immune system attacks the nerve-muscle connection in myasthenia gravis and how different patient groups are affected.
-
Biological age in myasthenia gravis: guiding who responds to treatment
A patient-friendly look at how a person’s biological age, not just their calendar age, might predict how MG patients respond to treatment and how treatments could even reduce biological aging.
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CapTURE-MG: A patient-friendly MG data toolkit in a common EHR
A multi-site effort to use a streamlined MG toolkit inside the Epic EHR to collect consistent, real-world information about myasthenia gravis from routine care.
-
Rare Disease Network for Myasthenia Gravis
A nationwide effort to improve diagnosis, monitoring, and trial readiness for people with myasthenia gravis through biomarker work and better care tools.
-
Understanding how autoimmune attacks cause myasthenia gravis
Researchers are studying how the immune system mistakenly targets the neuromuscular junction in myasthenia gravis to identify why the disease starts and how it progresses.
-
Mechanistically informed deep learning to study autoreactive B cells in Myasthenia Gravis
A study using advanced computer models to find hidden immune-cell signals in people with Myasthenia Gravis, including those who don’t yet show detectable antibodies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.