Using virtual resistance training to help patients with advanced upper gastrointestinal cancer during chemotherapy
Official title: Tele-resistance training during chemotherapy for advanced upper gastrointestinal cancer
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-10791823 · Data updated 2026-11-12
This study is looking at whether a virtual exercise program can help people with advanced upper gastrointestinal cancers feel stronger and better during chemotherapy, by making it easier for them to work out at home compared to regular exercise sessions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | March 15, 2022 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $161,973 |
| NIH project number | 5K22CA262352-03 |
| Project ID | NIH-10791823 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with advanced upper gastrointestinal cancers who are currently receiving chemotherapy.
✕Less likely to help
Patients who are not undergoing chemotherapy or those with early-stage cancers may not benefit from this research.
What this research studies
This research investigates the effectiveness of a virtual resistance training program for patients undergoing chemotherapy for advanced upper gastrointestinal cancers. The program aims to improve fitness, muscle health, and quality of life by providing a home-based exercise option that is more accessible than traditional supervised training. Participants will be randomly assigned to either the virtual training or usual care, allowing researchers to compare outcomes such as muscle strength, endurance, and fatigue levels. The goal is to determine if this innovative approach can enhance the overall treatment experience for cancer patients.
Why it matters
Potential benefit: If successful, this research could provide patients with a convenient way to maintain or improve their physical fitness and quality of life during chemotherapy.
How similar studies have gone: Previous studies have shown that home-based exercise programs can be beneficial for cancer patients, suggesting that this approach may also be effective.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Parker, Nathan H — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Parker, Nathan H
Related research
Other NIH-funded projects on the same topics.
-
Photodynamic lipids to boost chemotherapy for metastatic ovarian cancer
A patient-friendly approach tests a light-activated method to make ovarian cancer metastases more sensitive to chemotherapy.
-
Dual targeting of heart cell receptors to prevent chemotherapy heart damage
Atrial patients receiving the chemotherapy drug doxorubicin may be protected from heart damage by targeting two heart cell receptors at once.
-
A 3D ultrasound scanner to see early chemotherapy response in breast cancer
A new 3D ultrasound imaging method will be tested to see if it can quickly show whether breast cancer is responding to chemotherapy.
-
Non-invasive, microscopic biomarkers to detect CIPN in chemotherapy patients
This grant aims to develop a non-invasive imaging method to measure nerve changes in patients undergoing chemotherapy to better understand and monitor chemotherapy-induced peripheral neuropathy (CIPN).
-
Alternative NF-kB activation after chemotherapy in ovarian cancer
This grant studies how ovarian cancer might come back after chemotherapy by looking at specific signaling pathways in cancer cells and the tumor environment.
-
Genetic clues for doxorubicin heart risk using patient-derived heart cells
A research project tests how human heart cells grown from stem cells react to a common chemotherapy to see which genetic differences may raise the risk of heart damage.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.