Using virtual reality to treat phantom leg pain in amputees

Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain

NIH-funded research Albert Einstein Healthcare Network · NIH-10911243

This study is looking at how well virtual reality can help people who have phantom limb pain after an amputation, and it’s for anyone dealing with that kind of pain; participants will try either a special VR treatment or a standard VR pain relief option to see which works better, while also using advanced imaging to learn more about how these treatments affect the brain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlbert Einstein Healthcare Network NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10911243 on NIH RePORTER

What this research studies

This research investigates the effectiveness of virtual reality (VR) treatments for individuals experiencing phantom limb pain (PLP) after amputation. Participants will be randomized to receive either an active VR treatment or a commercially available VR pain treatment. The study aims to develop a home-based intervention for PLP and will utilize advanced MRI imaging to explore the neural mechanisms behind PLP and the efficacy of the treatments. By understanding these mechanisms, the research seeks to create predictive biomarkers for treatment response.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have undergone limb amputation and experience phantom limb pain.

Not a fit: Patients who do not have phantom limb pain or have not undergone limb amputation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel and effective treatment option for individuals suffering from phantom limb pain.

How similar studies have performed: Previous research has shown promising results using virtual reality for pain management, indicating potential success for this approach.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.