NIH-funded research R01 grant

Using virtual reality to help manage pain in patients with gastrointestinal cancer

Official title: Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Funded at Cedars-Sinai Medical Center · NIH-11067805 · Data updated 2026-11-12

This study is exploring how virtual reality can help people with severe abdominal pain from digestive tract cancers feel better and improve their quality of life by using VR goggles to experience relaxing environments.

More Randomized Controlled Trial research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startApril 5, 2021
Project endMarch 31, 2026
Funding year2025
Award (this year)$591,720
NIH project number5R01CA252211-05
Project IDNIH-11067805 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with gastrointestinal cancers who experience severe abdominal pain.

Less likely to help

Patients with non-cancer-related abdominal pain or those who do not experience significant pain may not benefit from this research.

What this research studies

This research investigates the use of virtual reality (VR) as a treatment for severe abdominal pain experienced by patients with digestive tract cancers. By wearing VR goggles, patients can immerse themselves in lifelike, three-dimensional environments that may help alleviate their pain and improve their overall quality of life. The study aims to assess the effectiveness of VR in reducing pain and enhancing patient-reported outcomes compared to traditional pain management methods. Participants will engage in VR sessions as part of their pain management plan, providing valuable data on its impact.

Why it matters

Potential benefit: If successful, this research could provide a non-opioid alternative for managing cancer-related abdominal pain, improving patients' quality of life.

How similar studies have gone: Previous studies have shown promising results for the use of virtual reality in managing pain, indicating potential for success in this novel application.

Where this research is happening

  • Cedars-Sinai Medical Center
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Spiegel, Brennan — Cedars-Sinai Medical Center
  • Study coordinator: Spiegel, Brennan

Related research

Other NIH-funded projects on the same topics.

  • VR-based CBT for IBS: at-home treatment idea with guided virtual reality therapy

    A pilot study will test whether a home-based VR cognitive behavioral therapy program helps people with irritable bowel syndrome feel better and manage symptoms compared with a sham VR experience.

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11357696

  • Using virtual reality to help manage irritable bowel syndrome symptoms

    This study is looking at whether a virtual reality program that offers therapy can help people with irritable bowel syndrome (IBS) manage their tummy pain and feel better overall, making it a convenient option for those who might not have easy access to traditional therapy.

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11140550

  • Using virtual reality to help manage chronic pain in cancer patients

    This study is exploring a new virtual reality device that helps cancer patients manage their chronic pain by taking them to relaxing virtual environments, and it aims to see how well this fun and calming tool works alongside regular pain treatments.

    NIH research Medstar Health Research Institute · Hyattsville, United States · NIH-11115251

  • Using virtual reality to help manage chronic low back pain

    This study is exploring how virtual reality can help adults with chronic low back pain feel better and move more, comparing it to regular pain treatments to see which works best for improving their daily lives.

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10896861

  • Using virtual reality to help manage chronic low back pain

    This study is exploring whether using virtual reality can help adults with chronic low back pain feel better and move more easily, comparing it to regular pain treatments like opioids, so you can see if this fun new approach might work for you!

    NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10683125

  • Cognitive behavioral therapy and trazodone for insomnia phenotypes with high blood pressure

    A clinical study tests how CBT-I and the sleep drug trazodone work for adults with insomnia and high blood pressure, focusing on a specific sleep duration pattern.

    NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11635771

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.