Using video and incentives to help people stick to TB treatment

Video DOT and Economic Incentives to promote adherence to LTBI therapy

['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-10656323

This study is looking to help people in Baltimore, especially those who were born outside the US and may have a hard time with treatment, stick to their latent tuberculosis (TB) medication by using a smartphone app that lets doctors check in and support them in their own language.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10656323 on ClinicalTrials.gov

What this research studies

This research focuses on improving adherence to treatment for latent tuberculosis (TB) among individuals in Baltimore, particularly those who are non-US-born and face various socioeconomic challenges. The study will utilize smartphone technology to implement video-directly observed therapy (vDOT), which allows healthcare providers to monitor patients' adherence in real-time while providing support and reminders in their preferred languages. By addressing barriers such as health literacy and access to care, the research aims to enhance treatment completion rates for latent TB, which is crucial for public health.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals over 21 years old who have been diagnosed with latent TB, particularly those from non-US backgrounds facing socioeconomic challenges.

Not a fit: Patients who do not have latent TB or those who are unable to access smartphone technology may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase the number of individuals completing their latent TB treatment, thereby reducing the risk of progression to active TB and improving overall public health.

How similar studies have performed: Previous research has shown success with similar smartphone-enabled interventions in promoting adherence to various treatments, indicating a promising approach for this study.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.