Using urine color to evaluate tuberculosis drug levels in children and adults
Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and Adults
This study is looking at how the color of your urine can help check the amount of TB medicine in both kids and adults, making it easier to get the right treatment, especially in places where medical facilities are hard to reach.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10993659 on NIH RePORTER |
What this research studies
This research investigates how urine color can be used to measure the levels of tuberculosis (TB) medications in both children and adults. By analyzing urine samples with a simple device, the study aims to provide a quick and effective way to monitor drug concentrations without the need for complex laboratory equipment. This approach is particularly important in areas where access to medical facilities is limited, as it could help tailor TB treatment to individual needs and improve outcomes. The research focuses on the drug rifampin, which is crucial for treating drug-sensitive TB.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adults diagnosed with active tuberculosis who are receiving treatment.
Not a fit: Patients who are not currently undergoing treatment for tuberculosis or those with drug-resistant strains may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective TB treatments by ensuring patients receive the right drug dosages based on their individual needs.
How similar studies have performed: Previous research has shown promising results using similar urine analysis techniques to monitor drug levels, indicating potential for success in this approach.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Heysell, Scott K — University of Virginia
- Study coordinator: Heysell, Scott K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.