Using ultrasound to treat obstructive hypertrophic cardiomyopathy
Minimally Invasive High Intensity Therapeutic Ultrasound for the Treatment of Obstructive Hypertrophic Cardiomyopathy
['FUNDING_SBIR_2'] · CORIDEA, LLC · NIH-10834827
This study is testing a new, less invasive ultrasound treatment for people with obstructive hypertrophic cardiomyopathy (oHCM) to help reduce heart blockage safely, especially for those who can't have traditional surgery.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORIDEA, LLC (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10834827 on ClinicalTrials.gov |
What this research studies
This research investigates a new treatment for obstructive hypertrophic cardiomyopathy (oHCM) using high-intensity therapeutic ultrasound. The approach involves a minimally invasive procedure that targets the heart's interventricular septum to reduce obstruction without the risks associated with traditional surgical methods. By utilizing a catheter inserted through the femoral vein, the treatment aims to ablate the problematic heart tissue while preserving the heart's electrical conduction system. This method could provide a safer alternative for patients who are not candidates for existing surgical options.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with obstructive hypertrophic cardiomyopathy who have not responded to medical management and are at risk of severe complications.
Not a fit: Patients with non-obstructive forms of hypertrophic cardiomyopathy or those who are not candidates for septal reduction therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and survival rates for patients with obstructive hypertrophic cardiomyopathy.
How similar studies have performed: While traditional surgical approaches have been successful, this novel ultrasound technique represents a new and untested method in the treatment of obstructive hypertrophic cardiomyopathy.
Where this research is happening
NEW YORK, UNITED STATES
- CORIDEA, LLC — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEVIN, HOWARD — CORIDEA, LLC
- Study coordinator: LEVIN, HOWARD
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.