Using ultrasound to restore vision in patients with Retinitis Pigmentosa
Sonogenetic Restoration of Vision for Retinitis Pigmentosa
['FUNDING_U01'] · NANOSCOPE TECHNOLOGIES, LLC · NIH-11077270
This study is looking at a new way to help people with Retinitis Pigmentosa regain some vision using ultrasound, which is a gentle sound wave technique, instead of surgery or gene therapy.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NANOSCOPE TECHNOLOGIES, LLC (nih funded) |
| Locations | 1 site (ARLINGTON, UNITED STATES) |
| Trial ID | NIH-11077270 on ClinicalTrials.gov |
What this research studies
This research explores a novel approach to restore vision in patients suffering from Retinitis Pigmentosa (RP) by using ultrasound stimulation. The study aims to sensitize specific retinal cells to ultrasound, allowing for targeted stimulation that could improve visual function. Unlike traditional methods that focus on gene therapy or invasive surgeries, this technique seeks to provide a non-invasive alternative to enhance vision in patients with retinal degeneration. The research will involve developing and testing this ultrasound-based method to determine its effectiveness and safety for potential clinical use.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Retinitis Pigmentosa who still have intact retinal ganglion cells.
Not a fit: Patients who have advanced degeneration of retinal cells beyond the point of intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive treatment option that restores vision for patients with Retinitis Pigmentosa.
How similar studies have performed: While ultrasound stimulation for retinal treatment is a novel approach, preliminary studies in related fields have shown promise, indicating potential for success.
Where this research is happening
ARLINGTON, UNITED STATES
- NANOSCOPE TECHNOLOGIES, LLC — ARLINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MOHANTY, SAMARENDRA KUMAR — NANOSCOPE TECHNOLOGIES, LLC
- Study coordinator: MOHANTY, SAMARENDRA KUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.