Using ultrasound to measure how stiff arteries are and its effects on brain health
Measuring arterial material properties using wave-based approaches with ultrasound and computational models
This study is looking at how stiff arteries might affect your brain health, using a special ultrasound technique to measure artery stiffness while also taking brain scans, with the goal of finding better ways to understand and manage changes in brain function related to heart health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11062415 on NIH RePORTER |
What this research studies
This research investigates how increased stiffness in arteries can impact brain health, particularly through changes detected by MRI. It employs a novel ultrasound technique called arterial dispersion ultrasound vibrometry (ADUV) to measure the mechanical properties of arteries in real-time. By correlating these measurements with brain imaging results, the study aims to create a tool that can predict and manage brain function changes due to arterial stiffness. This approach could lead to better understanding and management of cardiovascular and neurological health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with known cardiovascular conditions or those at risk for arterial stiffness and related brain health issues.
Not a fit: Patients without cardiovascular risk factors or existing brain health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive method to assess arterial health and its impact on brain function, potentially leading to improved prevention and treatment strategies for cardiovascular and neurological diseases.
How similar studies have performed: Previous research has shown promise in using ultrasound techniques for vascular evaluation, but this specific approach is relatively novel and untested in the context of correlating arterial stiffness with brain health.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Urban, Matthew William — Mayo Clinic Rochester
- Study coordinator: Urban, Matthew William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.