Using ultrasound to improve blood vessel formation in tissues

In Vivo Acoustic Patterning for Tissue Vascularization

['FUNDING_R01'] · UNIVERSITY OF ROCHESTER · NIH-11088746

This study is exploring a new ultrasound technique that helps grow blood vessels in tissues, which could be really helpful for people dealing with issues like poor blood flow or tissue damage.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ROCHESTER (nih funded)
Locations1 site (ROCHESTER, UNITED STATES)
Trial IDNIH-11088746 on ClinicalTrials.gov

What this research studies

This research focuses on developing a new ultrasound technology that can stimulate the growth of blood vessels directly within tissues. By using acoustic patterning, the researchers aim to organize cells in a way that promotes the formation of microvascular networks, which are crucial for tissue health and healing. The approach has shown promise in laboratory settings and early animal studies, where it successfully created functional blood vessel networks. The goal is to translate this technology for potential use in treating conditions related to poor blood flow and tissue damage.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients suffering from chronic conditions that result in poor blood circulation or those needing reconstructive surgery.

Not a fit: Patients with conditions that do not involve microvascular insufficiency or those who are not candidates for surgical interventions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved healing and recovery for patients with chronic diseases or those undergoing reconstructive surgeries.

How similar studies have performed: Previous studies have shown success with similar ultrasound-based techniques in laboratory settings, indicating potential for clinical application.

Where this research is happening

ROCHESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.