Using ultrasound to improve blood vessel formation in tissues
Official title: In Vivo Acoustic Patterning for Tissue Vascularization
Funded at University of Rochester · NIH-11088746 · Data updated 2026-11-12
This study is exploring a new ultrasound technique that helps grow blood vessels in tissues, which could be really helpful for people dealing with issues like poor blood flow or tissue damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | May 15, 2024 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $497,272 |
| NIH project number | 5R01EB035523-02 |
| Project ID | NIH-11088746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients suffering from chronic conditions that result in poor blood circulation or those needing reconstructive surgery.
✕Less likely to help
Patients with conditions that do not involve microvascular insufficiency or those who are not candidates for surgical interventions may not benefit from this research.
What this research studies
This research focuses on developing a new ultrasound technology that can stimulate the growth of blood vessels directly within tissues. By using acoustic patterning, the researchers aim to organize cells in a way that promotes the formation of microvascular networks, which are crucial for tissue health and healing. The approach has shown promise in laboratory settings and early animal studies, where it successfully created functional blood vessel networks. The goal is to translate this technology for potential use in treating conditions related to poor blood flow and tissue damage.
Why it matters
Potential benefit: If successful, this research could lead to improved healing and recovery for patients with chronic diseases or those undergoing reconstructive surgeries.
How similar studies have gone: Previous studies have shown success with similar ultrasound-based techniques in laboratory settings, indicating potential for clinical application.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Dalecki, Diane — University of Rochester
- Study coordinator: Dalecki, Diane
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.