Using ultrasound to improve bladder cancer treatment with nanoparticles
Ultrasound-based diagnostic and monitoring of bladder cancer treatment with drug released from nanoparticles
This study is exploring a new way to treat early-stage bladder cancer using tiny particles that help deliver chemotherapy drugs more effectively, so patients can get better results from their treatment.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nanomedtrix, LLC NIH-funded |
| Lab location | 1 site (Coralville, United States) |
| Project ID | NIH-10356881 on NIH RePORTER |
What this research studies
This research focuses on enhancing the treatment of bladder cancer by using nanoparticles that carry chemotherapy drugs. The approach involves using mesoporous silica nanoparticles to improve drug delivery, allowing for better penetration into tumors and longer contact time with cancer cells. Patients undergoing treatment for early-stage bladder cancer may benefit from this innovative method, which aims to overcome the limitations of current therapies. The research includes both in vivo and in vitro testing to ensure safety and efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with early-stage bladder cancer who are seeking improved treatment options.
Not a fit: Patients with advanced bladder cancer or those who are not eligible for intravesical therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for bladder cancer, reducing recurrence rates and improving patient outcomes.
How similar studies have performed: Previous research has shown promising results with nanoparticle-based drug delivery systems in cancer treatment, indicating potential for success in this approach.
Where this research is happening
Coralville, United States
- Nanomedtrix, LLC — Coralville, United States (Active)
Researchers
- Principal investigator: Assouline, Joe — Nanomedtrix, LLC
- Study coordinator: Assouline, Joe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.