Using ultrasound to control and visualize cellular functions
Sonogenetic Remote Control of Cellular Function
This study is looking at how ultrasound can help us see and control how cells work inside living tissues, which could improve treatments for conditions like brain issues and immune system problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Institute of Technology NIH-funded |
| Lab location | 1 site (Pasadena, United States) |
| Project ID | NIH-10897186 on NIH RePORTER |
What this research studies
This research explores the use of ultrasound as a method to visualize and manipulate cellular functions deep within living tissues. By leveraging the unique properties of sound waves, the study aims to overcome the limitations of light-based techniques, which struggle to penetrate tissues effectively. The approach could enable real-time observation and control of cellular processes in various biological contexts, including brain signaling and immune responses. This innovative methodology could also enhance the development of cell-based therapies by allowing for better monitoring and control of therapeutic agents after they are administered.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with conditions that affect deep tissues, such as neurological disorders or cancers, where enhanced cellular monitoring and therapy could be beneficial.
Not a fit: Patients with superficial conditions or those who do not require deep tissue intervention may not receive significant benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to groundbreaking advancements in how we visualize and control cellular functions, potentially improving treatments for various diseases.
How similar studies have performed: While the use of ultrasound in medical applications is established, this specific approach to controlling cellular functions using ultrasound is novel and has not been extensively tested.
Where this research is happening
Pasadena, United States
- California Institute of Technology — Pasadena, United States (Active)
Researchers
- Principal investigator: Shapiro, Mikhail — California Institute of Technology
- Study coordinator: Shapiro, Mikhail
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.