Using ultrasound signals to detect cancer in lymph nodes
In vivo Evaluation of Lymph Nodes Using Quantitative Ultrasound
['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11144345
This project tests a new ultrasound technique to help people with suspicious lymph nodes figure out if those nodes contain cancer while they get a medically needed biopsy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11144345 on ClinicalTrials.gov |
What this research studies
If you are scheduled for an ultrasound-guided fine-needle aspiration (FNA) of a suspicious lymph node, the team will use a modified clinical ultrasound scanner to capture extra raw echo data during your procedure. Researchers will run quantitative-ultrasound (QUS) algorithms on those echo signals to look for patterns that match metastatic cancer, primary lymphoma, or benign changes. The work is being done at multiple centers and will include a wider variety of diseases and a more diverse group of patients than earlier studies. The goal is to validate the approach so the software could be built into regular ultrasound machines used in clinics.
Who could benefit from this research
Good fit: Ideal candidates are people with suspicious or enlarged lymph nodes who are already scheduled for a clinically indicated ultrasound-guided FNA.
Not a fit: People without suspicious lymph nodes, or those not undergoing ultrasound-guided biopsy, are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this could make it easier to identify cancer in lymph nodes and improve staging and treatment choices without additional invasive tests.
How similar studies have performed: Earlier smaller studies from the same groups produced encouraging results, but this larger multicenter validation is a novel next step.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAMOU, JONATHAN — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: MAMOU, JONATHAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.