NIH-funded research Sbir 2 grant

Using ultra-fast imaging to improve electron FLASH radiation therapy

Official title: Ultra-fast imaging for the safe delivery of electron FLASH radiation therapy

Funded at Doseoptics, LLC · NIH-10708158 · Data updated 2026-11-12

This study is looking at ways to make a new type of cancer treatment called electron FLASH radiation therapy safer and more effective by using super-fast imaging to keep an eye on the treatment as it happens, which could help patients get better results while protecting healthy tissue.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionDoseoptics, LLC
NIH-funded
Lab location1 site (Lebanon, United States)
Project startSeptember 16, 2021
Project endAugust 31, 2025
Funding year2023
Award (this year)$999,998
NIH project number5R44CA268466-03
Project IDNIH-10708158 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are cancer patients who require radiation therapy as part of their treatment plan.

Less likely to help

Patients who are not undergoing radiation therapy or those with conditions that do not involve tumors may not benefit from this research.

What this research studies

This research focuses on enhancing the safety and effectiveness of electron FLASH radiation therapy, a cutting-edge treatment that minimizes damage to healthy tissues while targeting tumors. By developing ultra-fast imaging techniques, the project aims to monitor radiation delivery in real-time, addressing the challenges posed by the rapid dose rates of FLASH therapy. The approach involves leveraging advanced detection methods to ensure precise treatment delivery, which could significantly improve patient outcomes. The research is being conducted in collaboration with Dartmouth-Hitchcock, a clinical site that has pioneered the use of FLASH therapy.

Why it matters

Potential benefit: If successful, this research could lead to safer radiation therapy options with reduced side effects for cancer patients.

How similar studies have gone: Previous research has shown promising results with FLASH therapy, indicating its potential for significant advancements in cancer treatment.

Where this research is happening

  • Doseoptics, LLC
    Lebanon, United States
    Active

Researchers

  • Principal investigator: Bruza, Petr — Doseoptics, LLC
  • Study coordinator: Bruza, Petr

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.