Using tissue chips to improve treatment for a rare heart condition in children
Tissue chips for precision treatment of catecholaminergic polymorphic ventricular tachycardia
This study is looking at how tiny tissue models made from kids' own cells can help find the best treatments for catecholaminergic polymorphic ventricular tachycardia (CPVT), so doctors can offer safer and more personalized care without putting them through risky trials.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10914830 on NIH RePORTER |
What this research studies
This research investigates how patient-specific tissue chips can predict the effectiveness of treatments for catecholaminergic polymorphic ventricular tachycardia (CPVT), a serious heart condition in children. By creating tissue models from individual patients, the study aims to identify the best therapeutic options without exposing patients to the risks of traditional clinical trials. The approach focuses on understanding how different patients respond to treatments, which could lead to more personalized and effective care for those with CPVT.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with catecholaminergic polymorphic ventricular tachycardia.
Not a fit: Patients with other types of arrhythmias or those not diagnosed with CPVT may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatment options for children suffering from CPVT.
How similar studies have performed: Previous research has shown promise in using tissue chips for personalized medicine, indicating potential success for this novel approach.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Pu, William Tswenching — Boston Children's Hospital
- Study coordinator: Pu, William Tswenching
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.