Using tiny silica particles to improve surgery for high-risk prostate cancer
Molecular Phenotyping and Image-Guidance for Surgical Treatment of High-Risk Prostate Cancer Using Ultrasmall Silica Nanoparticles
This study is looking to help patients with high-risk prostate cancer by using special tiny particles that light up cancerous tissues during surgery, making it easier for doctors to see and remove all the cancer while reducing the chances of it coming back.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10784691 on NIH RePORTER |
What this research studies
This research focuses on enhancing surgical outcomes for patients with high-risk prostate cancer by developing advanced imaging techniques. It aims to create ultrabright silica nanoparticles that can specifically target and identify cancerous tissues during surgery. By using these nanoparticles, surgeons can better visualize and remove metastatic lymph nodes and ensure that no cancerous cells are left behind, potentially reducing the risk of recurrence. The approach combines molecular phenotyping with real-time imaging to improve surgical precision and patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are men diagnosed with high-risk prostate cancer who may require surgical intervention.
Not a fit: Patients with low-risk prostate cancer or those who are not candidates for surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective surgical treatments for high-risk prostate cancer, improving survival rates and reducing complications.
How similar studies have performed: Previous research has shown promise in using targeted imaging techniques for cancer surgery, suggesting that this approach could be effective.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Bradbury, Michelle S — Weill Medical Coll of Cornell Univ
- Study coordinator: Bradbury, Michelle S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.