Using tiny devices to improve wound healing
Nanofabricated Devices and Nanomedicine Approaches for Wound Healing
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10909402
This study is testing a new method that uses tiny electrical pulses to help your body heal wounds better by encouraging the growth of new blood vessels and nerve cells, starting with diabetic mice before it can be used in people like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10909402 on ClinicalTrials.gov |
What this research studies
This research focuses on a novel technique called tissue nanotransfection (TNT), which uses small electrical pulses to deliver genetic material directly into living tissues. By doing so, it aims to enhance the body's ability to heal wounds by promoting the formation of new blood vessels and nerve cells. The approach involves creating a specialized chip that can release engineered exosomes, which are tiny carriers that help in the healing process. The research will initially test this technology in diabetic mice before moving to human applications, ensuring it is safe and effective.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have wounds that are slow to heal, especially those with diabetes.
Not a fit: Patients with acute wounds that heal normally or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve wound healing, particularly for patients with diabetes or other conditions that impair healing.
How similar studies have performed: While the specific application of TNT in humans is novel, similar approaches using nanotechnology for wound healing have shown promise in preliminary studies.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XUAN, YI — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: XUAN, YI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.