Using time-based cancer immunograms to improve immunotherapy treatments
PROJECT 1: TIME-Based Spatiotemporal Cancer Immunograms Predictive for Immunotherapy-Targeted Therapy Sequential Combinations
['FUNDING_OTHER'] · INSTITUTE FOR SYSTEMS BIOLOGY · NIH-11191812
This study is looking at how tracking your immune response over time can help doctors figure out the best combination of immunotherapy treatments for cancer patients, so they can receive more personalized care that works better for them.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INSTITUTE FOR SYSTEMS BIOLOGY (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11191812 on ClinicalTrials.gov |
What this research studies
This research investigates how spatiotemporal cancer immunograms can be used to predict the effectiveness of sequential combinations of immunotherapy-targeted therapies. By analyzing the immune response over time, the study aims to identify optimal treatment strategies for patients with cancer. The approach involves collecting and analyzing data from cancer patients to create detailed immunograms that reflect their unique immune profiles. This personalized information could help tailor therapies to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing immunotherapy for cancer who may benefit from personalized treatment strategies.
Not a fit: Patients who are not receiving immunotherapy or those with conditions not related to cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapy treatments for cancer patients, enhancing their chances of recovery.
How similar studies have performed: While the specific approach of using time-based spatiotemporal immunograms is novel, similar research in personalized immunotherapy has shown promising results.
Where this research is happening
SEATTLE, UNITED STATES
- INSTITUTE FOR SYSTEMS BIOLOGY — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEATH, JAMES R. — INSTITUTE FOR SYSTEMS BIOLOGY
- Study coordinator: HEATH, JAMES R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.