Using time-based cancer immunograms to improve immunotherapy treatments
Official title: PROJECT 1: TIME-Based Spatiotemporal Cancer Immunograms Predictive for Immunotherapy-Targeted Therapy Sequential Combinations
Funded at Institute for Systems Biology · NIH-11191812 · Data updated 2026-11-12
This study is looking at how tracking your immune response over time can help doctors figure out the best combination of immunotherapy treatments for cancer patients, so they can receive more personalized care that works better for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Institute for Systems Biology NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 22, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $133,520 |
| NIH project number | 3U54CA274509-03S1 |
| Project ID | NIH-11191812 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing immunotherapy for cancer who may benefit from personalized treatment strategies.
✕Less likely to help
Patients who are not receiving immunotherapy or those with conditions not related to cancer may not benefit from this research.
What this research studies
This research investigates how spatiotemporal cancer immunograms can be used to predict the effectiveness of sequential combinations of immunotherapy-targeted therapies. By analyzing the immune response over time, the study aims to identify optimal treatment strategies for patients with cancer. The approach involves collecting and analyzing data from cancer patients to create detailed immunograms that reflect their unique immune profiles. This personalized information could help tailor therapies to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapy treatments for cancer patients, enhancing their chances of recovery.
How similar studies have gone: While the specific approach of using time-based spatiotemporal immunograms is novel, similar research in personalized immunotherapy has shown promising results.
Where this research is happening
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Institute for Systems Biology
Seattle, United States Active
Researchers
- Principal investigator: Heath, James R. — Institute for Systems Biology
- Study coordinator: Heath, James R.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.