Using telehealth to reduce loneliness in people with opioid use disorders

Addressing perceived social isolation as a novel therapeutic target among individuals with OUD using telehealth CBT

NIH-funded research University of Rochester · NIH-11117106

This study is looking at how feeling lonely affects people with opioid use disorders and is testing a new online therapy to help them feel more connected and improve their recovery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11117106 on NIH RePORTER

What this research studies

This research investigates how perceived social isolation, or loneliness, affects individuals with opioid use disorders (OUD) and explores a new treatment approach using Cognitive-Behavioral Therapy for Perceived Social Isolation (CBT-PSI) delivered via telehealth. The study aims to address negative beliefs and emotions that contribute to feelings of loneliness, which can lead to increased opioid use and relapse. Participants will be randomly assigned to receive either therapist-delivered CBT-PSI, therapist-delivered Health Education, or self-guided Health Education over six weekly sessions. By focusing on improving social support and reducing negative affect, the research seeks to enhance recovery outcomes for individuals struggling with OUD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorders who experience feelings of social isolation.

Not a fit: Patients who do not have opioid use disorders or those who do not experience perceived social isolation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental health and recovery outcomes for patients with opioid use disorders by reducing feelings of loneliness.

How similar studies have performed: While there is limited research specifically targeting perceived social isolation in individuals with OUD, effective interventions for loneliness have shown promise in other populations, suggesting potential for success in this novel approach.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.