Using technology to improve awareness of low blood sugar in type 1 diabetes patients
Using technology to define and mitigate risk of impaired awareness of hypoglycemia in patients with type 1 diabetes
This study is looking to help people with type 1 diabetes who have trouble sensing when their blood sugar is low by using special monitoring technology, and it will also see if new management tools can help them regain that awareness.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11077196 on NIH RePORTER |
What this research studies
This research aims to tackle the serious issue of severe hypoglycemia in patients with type 1 diabetes by identifying those with impaired awareness of hypoglycemia (IAH) using continuous glucose monitoring (CGM) technology. The study will analyze CGM data to find metrics that correlate with IAH and diminished counterregulatory responses. Additionally, it will explore whether modern management techniques, such as hybrid closed loop systems, can help restore awareness of hypoglycemia in these patients. By enrolling 112 subjects, the research will gather critical data on hormone responses and symptoms during hypoglycemic events.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who experience impaired awareness of hypoglycemia.
Not a fit: Patients who do not have type 1 diabetes or those who do not experience issues with hypoglycemia awareness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of severe hypoglycemia for patients with type 1 diabetes by improving their awareness of low blood sugar levels.
How similar studies have performed: Previous research has shown promise in using continuous glucose monitoring to improve diabetes management, indicating that this approach may yield beneficial results.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Pettus, Jeremy H — University of California, San Diego
- Study coordinator: Pettus, Jeremy H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.