Using stem cells to restore corneal function
Mesenchymal Stem Cells can Restore and Maintain Corneal Endothelial Function
['FUNDING_OTHER'] · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · NIH-11140570
This study is exploring how special cells from your body can be turned into eye cells that help with vision, aiming to find a new way to treat people with cornea problems and help them see better again.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR (nih funded) |
| Locations | 1 site (ALBUQUERQUE, UNITED STATES) |
| Trial ID | NIH-11140570 on ClinicalTrials.gov |
What this research studies
This research investigates how mesenchymal stem cells (MSCs) can be transformed into corneal endothelial cells (CECs) to treat diseases affecting the cornea. The study will evaluate different sources of MSCs, including those from bone marrow and adipose tissue, and assess their ability to regenerate corneal cells in laboratory and animal models. By understanding the differentiation process and the cells' integration with the cornea, the research aims to develop a new treatment that could restore vision in patients with corneal endothelial dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have corneal endothelial diseases.
Not a fit: Patients with conditions unrelated to corneal endothelial dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a novel treatment option for patients suffering from corneal endothelial diseases, potentially restoring their vision.
How similar studies have performed: Previous research has shown promise in using stem cells for regenerative therapies, suggesting potential success for this approach.
Where this research is happening
ALBUQUERQUE, UNITED STATES
- UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR — ALBUQUERQUE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ISLAM, MOHAMMAD MIRAZUL — UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- Study coordinator: ISLAM, MOHAMMAD MIRAZUL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.