Using stem cells to help muscles heal and regenerate
Skeletal Muscle Regeneration from Pluripotent Stem Cells
This study is exploring how special stem cells can help repair damaged muscles by turning into new muscle cells, and it's for anyone interested in new treatments for muscle injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11109672 on NIH RePORTER |
What this research studies
This research focuses on the potential of pluripotent stem cells, which can develop into various cell types, to regenerate skeletal muscle. The team has developed methods to create large quantities of muscle progenitor cells from these stem cells. When these cells are transplanted into damaged muscle tissue, they can form new muscle fibers and support long-term muscle regeneration. The study aims to understand how these cells behave in the adult muscle environment and how they can be optimized for therapeutic use.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with conditions that cause muscle degeneration or injury.
Not a fit: Patients with non-muscle related conditions or those who are not adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for muscle degeneration and injuries, improving recovery and quality of life for patients.
How similar studies have performed: Previous research has shown promising results using similar stem cell approaches for muscle regeneration, indicating potential for success in this area.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Perlingeiro, Rita C. R. — University of Minnesota
- Study coordinator: Perlingeiro, Rita C. R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.