Using stem cells to help heal muscle after rotator cuff injuries
Endogenous stem cells promote regeneration of muscle in rotator cuff repair
This study is looking at how certain stem cells in your body can help heal muscle tissue after a rotator cuff tear, especially considering how age and the size of the tear might affect this healing process, with the goal of improving recovery for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11044126 on NIH RePORTER |
What this research studies
This research investigates how endogenous stem cells, specifically fibro/adipogenic progenitor (FAP) cells, can aid in the regeneration of muscle tissue following rotator cuff tears. The study focuses on understanding the factors that influence the behavior of these cells in patients with rotator cuff injuries, particularly in relation to age and the size of the tear. By exploring the regenerative capabilities of FAPs, the research aims to improve clinical outcomes for patients undergoing rotator cuff repair. The approach includes analyzing the differentiation of these cells and their potential to enhance muscle recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from rotator cuff tears, particularly older adults or those with larger tears.
Not a fit: Patients with rotator cuff injuries who are not eligible for surgical repair or those with other complicating health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved healing and recovery for patients with rotator cuff injuries, enhancing their quality of life and ability to perform daily activities.
How similar studies have performed: While the specific application of FAPs in rotator cuff repair is novel, similar research has shown promise in using stem cells for muscle regeneration in other contexts.
Where this research is happening
San Francisco, United States
- Veterans Affairs Med Ctr San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Feeley, Brian — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Feeley, Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.