Using stem cells to create new blood vessels for heart disease treatment
Vascular Regeneration with Human Pluripotent Stem Cell-derived Vascular Cells and Engineering Approaches
This study is exploring a new way to help grow healthy blood vessels using special stem cells, which could be really helpful for people with heart problems caused by poor blood flow.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11008931 on NIH RePORTER |
What this research studies
This research focuses on developing new methods to regenerate blood vessels using human pluripotent stem cells, which can differentiate into various cell types. The approach involves creating endothelial cells from these stem cells to promote blood vessel formation, particularly in areas affected by ischemic cardiovascular diseases. The researchers have established a specialized culture system to produce these cells in a controlled environment, aiming to enhance their effectiveness in forming stable and functional blood vessels. This innovative strategy seeks to address the limitations of current therapies for patients with severe cardiovascular conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with severe ischemic cardiovascular conditions who have not responded well to existing treatments.
Not a fit: Patients with non-ischemic cardiovascular issues or those who are not candidates for cell therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from ischemic cardiovascular diseases by enhancing blood vessel regeneration.
How similar studies have performed: Previous studies have shown promise in using stem cells for vascular regeneration, indicating potential success for this approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Yoon, Young-Sup — Emory University
- Study coordinator: Yoon, Young-Sup
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.