Using stem cells to create models for type 1 diabetes treatment
Stem cell-based modeling of type 1 diabetes to accelerate translation of therapies
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11059406
This study is working on creating better models of type 1 diabetes using stem cells to help us understand the disease and find new treatments, so that people with T1D can benefit from improved therapies in the future.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-11059406 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced models of type 1 diabetes (T1D) using stem cells to better understand the disease and accelerate the development of new therapies. By creating a multi-cellular platform that combines stem cell-derived insulin-producing cells with various immune cells, researchers aim to mimic the autoimmune processes that destroy these cells. The project will optimize the differentiation of these cells and identify specific T cell receptors to enhance the effectiveness of potential treatments. This innovative approach seeks to bridge the gap between laboratory findings and clinical applications for T1D patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who are seeking new treatment options.
Not a fit: Patients with type 2 diabetes or other non-autoimmune forms of diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective therapies for managing or potentially reversing type 1 diabetes.
How similar studies have performed: Previous research has shown promise in using stem cell models to study autoimmune diseases, indicating potential for success in this novel approach.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARENT, AUDREY — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: PARENT, AUDREY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.