Using stem cell signals from the meninges to improve recovery after stroke
Meningeal Stem Cell Signals for Improving Sensorimotor and Cognitive Outcomes After Stroke
This study is looking at how special cells in the brain can help people recover better after a stroke, focusing on improving movement and thinking skills, and it aims to find new ways to support healing for stroke survivors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10744742 on NIH RePORTER |
What this research studies
This research investigates how signals from meningeal stem cells can enhance recovery of sensorimotor functions and cognitive abilities in patients who have suffered a stroke. The study focuses on understanding the migration and response of these stem cells in the brain after an ischemic event, aiming to identify therapeutic targets that could improve patient outcomes. By employing various methodologies, including molecular tools and in vivo imaging, the research seeks to uncover mechanisms that could restore vascular integrity and promote neurogenesis. Patients may benefit from insights that could lead to new treatment strategies for post-stroke deficits.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a stroke and are facing sensorimotor deficits or cognitive challenges as a result.
Not a fit: Patients who have not suffered a stroke or those with advanced neurodegenerative conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that significantly improve recovery and quality of life for stroke survivors.
How similar studies have performed: Other research has shown promise in utilizing stem cell signals for recovery after neurological injuries, suggesting a potential for success in this novel approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Hayakawa, Kazuhide — Massachusetts General Hospital
- Study coordinator: Hayakawa, Kazuhide
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.