Using statins to improve health outcomes in patients with compensated cirrhosis

Statin Therapy for patients with compensated Cirrhosis

NIH-funded research University of Michigan at Ann Arbor · NIH-10909074

This study is looking at whether taking statin medications can help people with compensated cirrhosis, a serious liver condition, by reducing their risk of serious health problems, and we're inviting patients from the University of Michigan's Hepatology practice to join us in this important research.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10909074 on NIH RePORTER

What this research studies

This research investigates the potential benefits of statin therapy for patients with compensated cirrhosis, a serious liver condition. The study aims to recruit a large group of patients from the University of Michigan's Hepatology practice to gather data on their health outcomes over time. By measuring various clinical indicators and incorporating patient-reported outcomes, the research seeks to determine if statins can help reduce the risk of severe complications associated with cirrhosis. The approach includes a multicenter consortium to enhance the diversity and size of the patient cohort.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with compensated cirrhosis who are being monitored for their liver health.

Not a fit: Patients with decompensated cirrhosis or those who are not eligible for statin therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatment options that improve the quality of life and health outcomes for patients with compensated cirrhosis.

How similar studies have performed: Previous epidemiological studies have suggested that statins may reduce the risk of complications in cirrhosis, but this research aims to provide the first prospective data on their effectiveness.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alcoholic Liver DiseasesCardiac DiseasesCardiac Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.