Using spinal cord stimulation to reduce pain from chemotherapy
Spinal cord stimulation for the attenuation of chemotherapy-induced peripheral neuropathy and enhanced chemotherapeutic efficacy
This study is looking at how spinal cord stimulation might help relieve the pain caused by chemotherapy-induced peripheral neuropathy, which many cancer patients experience, and aims to find ways to make this treatment even more effective.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10861786 on NIH RePORTER |
What this research studies
This research investigates the use of spinal cord stimulation (SCS) as a treatment for chemotherapy-induced peripheral neuropathy (CIPN), a painful side effect of cancer treatment. The study aims to understand how SCS can alleviate pain and potentially enhance the effectiveness of chemotherapy. Researchers will explore the electrical settings of SCS and its effects on the nervous system and immune response in both animal models and human tissues. By examining these mechanisms, the research seeks to provide insights into improving pain management for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients experiencing chemotherapy-induced peripheral neuropathy.
Not a fit: Patients who are not undergoing chemotherapy or do not experience neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce pain for patients undergoing chemotherapy and improve their overall treatment experience.
How similar studies have performed: Previous studies have shown promising results with spinal cord stimulation for various neuropathic pain conditions, suggesting potential for success in this novel application.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Sivanesan, Eellan — Johns Hopkins University
- Study coordinator: Sivanesan, Eellan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.