Using spinal cord stimulation and exercise to improve movement in people with spinal cord injuries

Neural plasticity by spinal cord stimulation and training in people with spinal cord injury

['FUNDING_CAREER'] · WASHINGTON UNIVERSITY · NIH-10925176

This study is looking at how using electrical stimulation on the spinal cord along with exercise can help people with spinal cord injuries move better, and it’s designed for individuals who want to improve their movement and recovery.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10925176 on ClinicalTrials.gov

What this research studies

This research investigates how electrical spinal cord stimulation (SCS) combined with exercise training can help restore movement in individuals with spinal cord injuries (SCI). Participants will engage in leg training sessions while using a computer interface to control movements, allowing researchers to assess changes in neural activity and motor function. The study aims to understand the mechanisms behind improvements in movement and how specific training can enhance these effects. By measuring neural excitability before and after training, the research seeks to provide insights into long-term recovery processes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with spinal cord injuries who are seeking to regain motor function and improve their mobility.

Not a fit: Patients with complete paralysis or those who do not have spinal cord injuries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new rehabilitation strategies that significantly improve mobility and quality of life for individuals with spinal cord injuries.

How similar studies have performed: Previous research has shown promising results using similar approaches of spinal cord stimulation combined with rehabilitation exercises, indicating potential for success in this area.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.