Using special nanospheres to improve wound healing in breast cancer patients after radiation therapy.
Official title: Fibrinogen-coated albumin nanospheres for mitigation of irradiation-induced wound healing impairment in breast cancer patients.
Funded at Fibroplate, INC. · NIH-11062568 · Data updated 2026-11-12
This study is testing a new way to help heal skin injuries in breast cancer patients who have had radiation therapy by using tiny particles that can boost the body's natural healing process.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fibroplate, INC. NIH-funded |
| Lab location | 1 site (Las Vegas, United States) |
| Project start | September 12, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $386,470 |
| NIH project number | 1R43CA291219-01A1 |
| Project ID | NIH-11062568 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer patients who are experiencing impaired wound healing after radiation therapy.
✕Less likely to help
Patients who have not undergone radiation therapy or those with wounds unrelated to cancer treatment may not benefit from this research.
What this research studies
This research investigates a new treatment using Fibrinogen-coated Albumin nanospheres to enhance wound healing in breast cancer patients who have undergone radiation therapy. Radiation can cause significant skin injuries and ulcers, which complicate recovery and delay further treatment. The approach involves injecting these nanospheres to promote the healing process by mobilizing specific cells that aid in tissue repair and regulating inflammatory responses. The study aims to evaluate the effectiveness of this treatment in preclinical settings before it can be applied to patients.
Why it matters
Potential benefit: If successful, this research could significantly improve wound healing for breast cancer patients undergoing radiation therapy, potentially leading to better treatment outcomes.
How similar studies have gone: Previous studies have shown promise in using similar approaches to enhance wound healing, suggesting potential for success in this novel application.
Where this research is happening
-
Fibroplate, INC.
Las Vegas, United States Active
Researchers
- Principal investigator: Yen, Richard — Fibroplate, INC.
- Study coordinator: Yen, Richard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.