Using special immune cells to fight HIV

Harnessing Stem-like CD8 T Cells for Immunotherapies to Eradicate HIV Reservoirs

NIH-funded research Ut Southwestern Medical Center · NIH-11046355

This study is exploring new ways to boost certain immune cells to help the body fight and potentially get rid of HIV, offering hope for better treatment options for people living with the virus.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-11046355 on NIH RePORTER

What this research studies

This research focuses on harnessing stem-like CD8 T cells to develop new immunotherapies aimed at eradicating HIV reservoirs in the body. By enhancing the function of these immune cells, the research aims to improve the body's ability to target and eliminate HIV-infected cells. Patients may benefit from innovative treatment options that could lead to better management or potential eradication of HIV. The approach involves advanced immunological techniques and may pave the way for more effective therapies against HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who have not achieved viral suppression or have persistent viral reservoirs despite treatment.

Not a fit: Patients who are HIV-negative or those with advanced AIDS who are not responding to any form of treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to groundbreaking therapies that significantly improve the management of HIV and potentially eradicate the virus from the body.

How similar studies have performed: Other research has shown promise in using immunotherapy approaches to target HIV, indicating that this area of study has potential for significant advancements.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.