Using special hydrogels to improve healing of chronic wounds
Official title: Combining soluble and bound factors in microstructured hydrogels to promote chronic wound angiogenesis and healing
Funded at University of New Hampshire · NIH-11127584 · Data updated 2026-11-12
This study is looking at how special gels that combine different healing ingredients can help chronic wounds heal better, and it could lead to new treatments that make recovery easier for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Hampshire NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | July 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $373,582 |
| NIH project number | 5R35GM155450-02 |
| Project ID | NIH-11127584 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic wounds that are slow to heal.
✕Less likely to help
Patients with acute wounds or those whose wounds are healing normally may not benefit from this research.
What this research studies
This research investigates how combining soluble and bound factors in specially designed hydrogels can enhance the healing process of chronic wounds. By mimicking the natural environment of wound healing, the study aims to understand how these factors influence cell behavior and blood vessel formation. Patients may benefit from a new treatment approach that promotes better healing outcomes through advanced biomaterials and innovative techniques. The research focuses on the interaction between these factors to optimize their effects on wound healing.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic wounds, enhancing healing and reducing complications.
How similar studies have gone: Previous research has shown promise in using biomaterials for wound healing, indicating that this approach may lead to significant advancements.
Where this research is happening
-
University of New Hampshire
Durham, United States Active
Researchers
- Principal investigator: Li, Linqing — University of New Hampshire
- Study coordinator: Li, Linqing
Related research
Other NIH-funded projects on the same topics.
-
Diabetic Foot Ulcer Healing Network at the University of Arizona
A NIH-supported project at the University of Arizona aims to improve healing of diabetic foot ulcers by studying biomarkers and running high-quality clinical trials.
-
Understanding how skin layers coordinate healing after injury
Researchers are studying how different layers of adult skin coordinate rapid healing after injury to prevent infection and chronic wounds.
-
Immunomodulatory therapy to speed up healing after oral cavity injuries in kids
A new approach using a drug called FTY720 aims to improve healing and reduce pain after oral injuries or palate surgery in children.
-
How diabetic wounds let Group B Streptococcus cause infections
Researchers are learning how high blood sugar, immune changes, and other bacteria in diabetic wounds help Group B Streptococcus grow and cause worse infections in people with diabetes.
-
Understanding how skin cells exchange harmful chemicals to cause injury and wound repair
A research project aims to uncover how certain chemical agents damage human skin and what happens in the early stages of blistering and inflammation.
-
Intestinal mucosal wound healing in humans
A patient-friendly look at how the lining of the gut repairs itself after injury and why this matters for conditions like inflammatory bowel disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.