Using special fluorescent probes to improve brain surgery for tumor removal
White matter tract-specific near-infrared fluorescence probes for in vivo fluorescence guided white matter tractography
['FUNDING_R21'] · UNIVERSITY OF TEXAS MED BR GALVESTON · NIH-10873839
This study is testing a special tool that helps surgeons see important brain pathways more clearly during tumor surgery, making it easier to remove tumors while keeping healthy brain tissue safe.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS MED BR GALVESTON (nih funded) |
| Locations | 1 site (GALVESTON, UNITED STATES) |
| Trial ID | NIH-10873839 on ClinicalTrials.gov |
What this research studies
This research focuses on developing near-infrared fluorescent probes that can help surgeons visualize white matter tracts in the brain during tumor surgery. By enhancing the visibility of these critical pathways, the probes aim to improve the accuracy of tumor resections while preserving essential brain functions. The study will involve testing these probes in a clinical setting to assess their effectiveness in guiding surgical procedures and minimizing damage to surrounding healthy tissue.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with primary brain tumors who are scheduled for surgical intervention.
Not a fit: Patients with brain tumors who are not candidates for surgery or those with non-primary brain tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer brain surgeries with better outcomes for patients with brain tumors.
How similar studies have performed: Previous research has shown promise in using fluorescence-guided techniques in surgery, indicating potential for success with this novel approach.
Where this research is happening
GALVESTON, UNITED STATES
- UNIVERSITY OF TEXAS MED BR GALVESTON — GALVESTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VALDES QUEVEDO, PABLO ANDRES — UNIVERSITY OF TEXAS MED BR GALVESTON
- Study coordinator: VALDES QUEVEDO, PABLO ANDRES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.