Using special fluorescent probes to help surgeons see and preserve cranial nerves during surgery

Fluorescence Guided Surgery using Near Infrared Nerve-specific Probes for Cranial Nerve Preservation

['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11084320

This study is looking at new ways to help surgeons see important nerves better during brain surgeries, which could help prevent injuries and make recovery easier for patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-11084320 on ClinicalTrials.gov

What this research studies

This research focuses on improving surgical outcomes by enhancing the visualization of cranial nerves during skull base surgeries. It aims to develop and utilize fluorescence-guided surgery techniques with nerve-specific probes to prevent nerve injuries, which are a significant source of complications and morbidity. By integrating advanced imaging techniques, the study seeks to provide surgeons with better tools to identify and preserve these critical nerves during minimally invasive procedures. This approach could lead to improved patient safety and quality of life post-surgery.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients undergoing skull base surgeries who are at risk of cranial nerve injury.

Not a fit: Patients who are not undergoing surgical procedures involving cranial nerves may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of nerve injuries during surgeries, leading to better recovery and quality of life for patients.

How similar studies have performed: Previous research has shown promise in using fluorescence-guided techniques in surgery, indicating potential success for this novel approach.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.