Using soy isoflavones to reduce asthma risk in infants
Soy Isoflavones for Inner City Infants at Risk for Asthma (SIRA)
['FUNDING_U01'] · LURIE CHILDREN'S HOSPITAL OF CHICAGO · NIH-11072972
This study is looking at whether giving soy isoflavones to babies who are at higher risk for asthma can help prevent them from developing asthma and allergies during their first year of life.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LURIE CHILDREN'S HOSPITAL OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11072972 on ClinicalTrials.gov |
What this research studies
This research investigates whether soy isoflavones can help prevent asthma in infants who are genetically at risk. It involves a randomized trial where high-risk infants will receive either soy isoflavones or a placebo during their first year of life. The study aims to determine if this supplementation can lower the chances of developing asthma-related airway inflammation and allergic responses. By focusing on infants with a specific genetic profile, the research seeks to provide targeted prevention strategies for asthma.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants under one year old who have a specific genetic predisposition to asthma.
Not a fit: Patients who are not genetically predisposed to asthma or are older than one year may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of asthma development in at-risk infants.
How similar studies have performed: Previous research has shown that soy isoflavones can reduce asthma exacerbations in individuals with the relevant genetic profile, suggesting potential success for this approach.
Where this research is happening
CHICAGO, UNITED STATES
- LURIE CHILDREN'S HOSPITAL OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KUMAR, RAJESH — LURIE CHILDREN'S HOSPITAL OF CHICAGO
- Study coordinator: KUMAR, RAJESH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.