Using sound waves to improve non-invasive tissue treatment methods
Acoustic Cavitation Emission (ACE) Feedback Methods for Monitoring Histotripsy-Induced Tissue Fractionation In Situ
This study is looking to improve a gentle treatment called histotripsy that uses sound waves to break down tissue, and it's for anyone who might benefit from safer and more effective procedures by helping doctors predict how well the treatment will work based on the sounds it makes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11124754 on NIH RePORTER |
What this research studies
This research focuses on enhancing a non-invasive treatment called histotripsy, which uses ultrasound to break down and liquefy tissues. The team aims to develop new metrics that can predict how effective this treatment will be based on the sound waves generated during the process. By monitoring these sound signals, they hope to better understand how different tissues respond to the treatment, ensuring safer and more effective procedures for patients. This work is crucial as it seeks to establish reliable methods for assessing tissue damage during treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients requiring non-invasive tissue ablation therapies, particularly those with conditions that could benefit from histotripsy.
Not a fit: Patients with conditions that do not involve tissue ablation or those who are not candidates for ultrasound-based therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise and effective non-invasive treatments for various medical conditions.
How similar studies have performed: Previous research has shown promise in using ultrasound for tissue ablation, but this specific approach to monitoring cavitation effects is novel.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Sukovich, Jonathan Robert — University of Michigan at Ann Arbor
- Study coordinator: Sukovich, Jonathan Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.