Using social networks to find undiagnosed HIV in men and reduce stigma

Site-randomized trial of a novel social network recruitment intervention to locate more undiagnosed positive cases of HIV, increase HIV testing among men, and reduce HIV-related stigma

NIH-funded research University of Illinois at Chicago · NIH-11403814

This project asks people newly diagnosed with HIV to invite people they know for testing so more men with undiagnosed HIV can be found, linked to care, and stigma around testing reduced.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-11403814 on NIH RePORTER

What this research studies

If you take part, someone newly diagnosed with HIV will be asked to invite members of their wider social network — not just recent sexual partners — who they think might be unaware of their HIV status. Those network members will be offered HIV testing and, if positive, referred to treatment or linked to follow-up testing if negative. The approach is being rolled out at some clinics and compared with usual outreach at other clinics to see which reaches more undiagnosed people and lowers stigma. The intervention explicitly asks people to recruit non-risk partners to reduce blame and make men more comfortable getting tested.

Who could benefit from this research

Good fit: Ideal participants include adults in affected South African communities — especially people newly diagnosed with HIV who can invite contacts and men who avoid testing.

Not a fit: People who do not live near participating clinics, are unwilling to be contacted by peers, or decline testing are unlikely to benefit directly from this work.

Why it matters

Potential benefit: Could help find more men living with undiagnosed HIV, get them into treatment sooner, and lower HIV-related stigma that keeps people from testing.

How similar studies have performed: Peer and network-based recruitment has previously increased HIV testing, but this expanded, stigma-focused approach that includes non-risk contacts is a newer strategy.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.