Using smell to assess risks of Alzheimer's disease in diverse populations

Novel olfactory-based approach to measure risks of Alzheimer's disease and related dementias in diverse populations

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11038319

This study is exploring a new way to check memory in people with Alzheimer's and similar conditions by using smells, making it easier for everyone to understand and use, especially in communities with different reading skills.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11038319 on NIH RePORTER

What this research studies

This research investigates a novel method of measuring memory function related to Alzheimer's disease and related dementias by using olfactory cues. It aims to develop an olfactory-based assessment tool that can be easily understood and utilized across different populations, especially where literacy levels vary. The study will implement the Percepts of Odor Episodic Memory (POEM) protocol in a longitudinal survey of individuals affected by the 2004 Indian Ocean tsunami, allowing for a comprehensive evaluation of memory function. By focusing on olfactory memory, the research seeks to provide a more accessible way to identify cognitive deficits in aging populations worldwide.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults from diverse backgrounds, particularly those living in areas with varying literacy levels.

Not a fit: Patients who are not elderly or do not have concerns related to Alzheimer's disease or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and universally applicable method for early detection of Alzheimer's disease and related dementias.

How similar studies have performed: Previous research has shown promise in using olfactory assessments for cognitive function, suggesting that this approach could be a valuable addition to existing methods.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.