Using smartphones to spot mood changes and future depression risk in teens

Harnessing smartphones for real-time detection of affective disturbance and future depression risk in adolescents

['FUNDING_R01'] · MCLEAN HOSPITAL · NIH-11269159

This project uses teens' smartphones to track daily behavior and mood-linked signals so teens at risk for depression can be noticed earlier.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMCLEAN HOSPITAL (nih funded)
Locations1 site (BELMONT, UNITED STATES)
Trial IDNIH-11269159 on ClinicalTrials.gov

What this research studies

You'll install an app that passively collects phone data like activity, location, sleep patterns, phone use, and social interaction proxies while also reporting brief mood ratings. Researchers will combine these continuous sensor streams with self-reported mood to detect moments of high negative affect and build models that predict future risk of major depression. The work focuses on adolescents and follows them over time to capture real-life mood changes as they happen. Data collection is continuous and unobtrusive, aiming to identify patterns that could signal worsening mental health before clinical symptoms fully emerge.

Who could benefit from this research

Good fit: Ideal candidates are adolescents (roughly middle- to late-teen ages) who own a smartphone and are willing to share passive phone data and brief mood reports over time.

Not a fit: Teens who do not own or use a smartphone, cannot share phone data, or who need immediate intensive psychiatric care may not benefit from this research approach.

Why it matters

Potential benefit: If successful, this approach could help spot acute mood problems sooner and give teens, families, or clinicians a chance to act before depression develops or worsens.

How similar studies have performed: Prior digital-phenotyping studies have shown promise for detecting mood changes from phone data, but predicting future depression onset in adolescents remains relatively new and is still being tested.

Where this research is happening

BELMONT, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.