NIH-funded research R01 grant

Using smartphone apps to monitor mood changes in bipolar disorder

Official title: Detecting dynamic fluctuations in emotion, mood, and functioning: A digital phenotyping approach to clinical monitoring in bipolar disorder

Funded at University of Michigan at Ann Arbor · NIH-11000842 · Data updated 2026-11-12

This study is exploring how a new smartphone app can help people with bipolar disorder keep track of their moods in real-time, making it easier to understand their emotional ups and downs over six months without needing constant check-ins.

More Bipolar Disorder research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startDecember 13, 2023
Project endOctober 31, 2028
Funding year2025
Award (this year)$633,784
NIH project number5R01MH130411-02
Project IDNIH-11000842 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with bipolar disorder who experience mood instability.

Less likely to help

Patients who do not have bipolar disorder or those with stable mood patterns may not benefit from this research.

What this research studies

This research investigates how smartphone applications can be used to continuously monitor emotional patterns in individuals with bipolar disorder. By utilizing a method called ecological momentary assessment (EMA) alongside a new app called PRIORI, the study aims to unobtrusively track mood fluctuations and predict mood symptoms. Participants will engage in a six-month protocol where their emotional states are assessed through passive monitoring of ambient audio, allowing for a more accurate understanding of their mood dynamics without the burden of frequent assessments.

Why it matters

Potential benefit: If successful, this research could lead to improved monitoring and management of mood symptoms in patients with bipolar disorder.

How similar studies have gone: Previous research has shown promise in using digital phenotyping and mobile applications for monitoring mental health, indicating a potential for success in this approach.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Mcinnis, Melvin G — University of Michigan at Ann Arbor
  • Study coordinator: Mcinnis, Melvin G

Related research

Other NIH-funded projects on the same topics.

  • Understanding how mood swings happen in bipolar disorder

    Researchers are testing a high-tech brain imaging approach to map how emotions flare and fade in people with bipolar disorder.

    NIH research Laureate Institute for Brain Research · Tulsa, United States · NIH-11413545

  • Smartphone-based mood and emotion monitoring for bipolar disorder

    This project uses an Android app that passively tracks voice and behavior to spot mood and emotion changes in people with bipolar disorder.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11231253

  • Investigating how light sensitivity affects sleep and mood in bipolar disorder

    This study is looking at how being sensitive to light might affect sleep, mood, and energy levels in people with bipolar disorder, and it hopes to find ways to improve treatment based on these findings.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11079479

  • Identifying brain targets for treating mood disorders in bipolar patients

    This study is looking at how a treatment called transcranial magnetic stimulation (TMS) can be improved for people with bipolar disorder by finding the best spots in the brain to help with mood swings, and it involves some brain scans and tests to make sure the chosen spots are effective.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-10896349

  • Doula support to improve mood and anxiety health for rural mothers

    A rural-focused program tests whether birth doulas can boost confidence, support, and maternal health for new mothers with mood and anxiety concerns.

    NIH research University of Montana · Missoula, United States · NIH-11632168

  • Detailed brain mapping for bipolar disorder and major depression

    Researchers are using thousands of MRI scans to map fine-grained brain structure differences in people with bipolar disorder and major depression compared with people without these conditions.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11512325

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.