Using rhythmic light therapy to improve sleep and brain function in Alzheimer's patients

The Use of Rhythmic Light Therapy to Entrain Gamma Oscillations and the Circadian System in Patients with Alzheimer's Disease and Related Dementias (ADRD)

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10685526

This study is looking at how special light therapy can help people with Alzheimer's and related conditions sleep better and think more clearly, making their daily lives a little easier and more enjoyable.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10685526 on ClinicalTrials.gov

What this research studies

This research investigates how rhythmic light therapy can help improve sleep patterns and cognitive function in patients with Alzheimer's disease and related dementias. The approach involves using specific light frequencies to promote healthy brain activity and synchronize the body's internal clock. By targeting both sleep-wake cycles and brain oscillations, the study aims to enhance overall well-being in individuals with mild cognitive impairment and mild Alzheimer's. Participants will be exposed to tailored lighting interventions designed to optimize their circadian rhythms and cognitive performance.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults diagnosed with mild cognitive impairment or mild Alzheimer's disease.

Not a fit: Patients with advanced Alzheimer's disease or other severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved sleep quality and cognitive function for patients with Alzheimer's disease.

How similar studies have performed: Previous studies have shown promising results with similar light therapy approaches, indicating potential for success in this research.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.