Using retinal blood vessel changes to predict brain degeneration in multiple sclerosis
Retinal microvasculature as a predictor of neurodegeneration in multiple sclerosis
['FUNDING_OTHER'] · PORTLAND VA MEDICAL CENTER · NIH-10938028
This study is looking at how changes in the tiny blood vessels in the eye can help us understand brain changes in people with multiple sclerosis, and it’s for anyone with MS who wants to help find new ways to slow down these changes.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PORTLAND VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-10938028 on ClinicalTrials.gov |
What this research studies
This research investigates how changes in the small blood vessels of the retina can indicate neurodegeneration in individuals with multiple sclerosis (MS). By utilizing advanced imaging techniques like optical coherence tomography angiography (OCTA), the study aims to correlate these retinal changes with both self-reported symptoms and clinical measures of neurodegeneration. Participants will undergo a series of neurological and visual exams, along with questionnaires to evaluate their quality of life. The ultimate goal is to identify potential treatments that could slow down neurodegeneration in MS patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who are experiencing neurodegenerative symptoms.
Not a fit: Patients without a diagnosis of multiple sclerosis or those who do not exhibit neurodegenerative symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to monitor and potentially treat neurodegeneration in multiple sclerosis.
How similar studies have performed: Previous research has shown that retinal imaging can be a valuable tool in understanding neurodegenerative diseases, suggesting that this approach may yield meaningful insights.
Where this research is happening
PORTLAND, UNITED STATES
- PORTLAND VA MEDICAL CENTER — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SILBERMANN, ELIZABETH — PORTLAND VA MEDICAL CENTER
- Study coordinator: SILBERMANN, ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.