Using resistance training and creatine to improve physical function in colorectal cancer survivors with muscle loss

The Feasibility and Acceptability of Resistance Training and Creatine Supplementation to Promote Physical Function in Sarcopenic Colorectal Cancer Survivors

NIH-funded research University of South Carolina at Columbia · NIH-10867353

This study is looking at whether doing strength training along with taking creatine can help colorectal cancer survivors who are losing muscle strength and mass feel better and move easier after their treatment.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of South Carolina at Columbia NIH-funded
Lab location1 site (Columbia, United States)
Project IDNIH-10867353 on NIH RePORTER

What this research studies

This research investigates how combining resistance training with creatine supplementation can help colorectal cancer survivors who are experiencing sarcopenia, which is the loss of muscle mass and function. The study will assess the feasibility and acceptability of this combined approach compared to resistance training alone. Participants will engage in a randomized controlled trial to evaluate how these interventions can enhance their physical function and overall well-being after cancer treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are colorectal cancer survivors who are experiencing sarcopenia and are looking to improve their physical function.

Not a fit: Patients who are not colorectal cancer survivors or those without sarcopenia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve physical function and quality of life for colorectal cancer survivors suffering from muscle loss.

How similar studies have performed: Previous research has shown that creatine supplementation can effectively enhance the benefits of resistance training in older adults and clinical populations, indicating a promising approach for this study.

Where this research is happening

Columbia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer Survivor
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.