Using real-world data from multiple countries to improve biosimilar product approvals

Bridging the Gap: Using Foreign Real-World Data to Inform Interchangeable Biosimilar Approvals

NIH-funded research Academy of Managed Care Pharmacy, INC. · NIH-10832215

This study is looking at how real-world information from the U.S., Italy, and Denmark can help make it easier and faster for new biosimilar medicines to get approved, so patients can have more options for their treatments.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionAcademy of Managed Care Pharmacy, INC. NIH-funded
Lab location1 site (Alexandria, United States)
Project IDNIH-10832215 on NIH RePORTER

What this research studies

This research investigates how real-world data (RWD) from the U.S., Italy, and Denmark can be utilized to enhance the regulatory approval process for interchangeable biosimilars. By evaluating the feasibility and validity of using foreign RWD, the study aims to develop a common data model and shared protocol for conducting biosimilar interchangeability studies. The findings will inform recommendations for the FDA on integrating international data into their decision-making processes, potentially leading to more efficient approvals of biosimilars.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who may benefit from biosimilar medications, particularly those with conditions requiring biologic treatments.

Not a fit: Patients who are not seeking treatment with biosimilars or those who do not have access to these medications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could streamline the approval process for biosimilars, making them more accessible and affordable for patients.

How similar studies have performed: While the use of real-world data in regulatory processes is gaining traction, this specific approach of integrating foreign RWD for biosimilar approvals is relatively novel and has not been extensively tested.

Where this research is happening

Alexandria, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.