Using rare genetic causes to improve understanding and treatment of neuropsychiatric disorders
Leveraging rare genetic etiologies to advance knowledge and treatment of neuropsychiatric disorders
This study is looking at how rare genetic disorders might affect mental health conditions like schizophrenia, bipolar disorder, and autism, and it's for people with unique genetic profiles who want to help us understand how these genes influence symptoms and treatment options.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Geisinger Clinic NIH-funded |
| Lab location | 1 site (Danville, United States) |
| Project ID | NIH-10597665 on NIH RePORTER |
What this research studies
This research investigates how rare genetic disorders contribute to neuropsychiatric conditions like schizophrenia, bipolar disorder, and autism. By leveraging advanced genomic technologies, the study aims to identify and characterize the genetic factors that influence these disorders. Researchers will recruit individuals with rare genetic profiles from large clinical populations to better understand the variability in symptoms and outcomes. The goal is to establish a clearer link between genetics and neuropsychiatric symptoms, potentially leading to improved treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neuropsychiatric disorders who have rare genetic etiologies.
Not a fit: Patients without a diagnosed neuropsychiatric disorder or those with common genetic profiles may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments tailored to the genetic profiles of patients with neuropsychiatric disorders.
How similar studies have performed: Previous research has successfully used similar genetic approaches to advance understanding and treatment in other medical fields, suggesting potential for success in this area as well.
Where this research is happening
Danville, United States
- Geisinger Clinic — Danville, United States (Active)
Researchers
- Principal investigator: Martin, Christa Lese — Geisinger Clinic
- Study coordinator: Martin, Christa Lese
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.