Using pulsed ultrasound to slow down kidney disease progression.
Official title: Effect of Pulsed Splenic Ultrasound on delaying Chronic Kidney Disease Progression through a Neuroimmune Mechanism.
Funded at University of Virginia · NIH-10998571 · Data updated 2026-11-12
This study is looking at how using pulsed ultrasound on the spleen might help slow down kidney problems for people with chronic kidney disease, offering a gentle treatment option that could improve kidney health without the side effects of regular medications.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $38,198 |
| NIH project number | 1F30DK138782-01A1 |
| Project ID | NIH-10998571 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with a history of acute kidney injury or those at risk of developing chronic kidney disease.
✕Less likely to help
Patients with advanced chronic kidney disease or those who do not have a history of acute kidney injury may not benefit from this research.
What this research studies
This research investigates the use of pulsed ultrasound directed at the spleen to potentially delay the progression of chronic kidney disease (CKD). By targeting the immune response through neuroimmune mechanisms, the study aims to reduce inflammation that can worsen kidney function after acute kidney injury. Patients may benefit from a non-invasive treatment option that could help manage their kidney health without the side effects associated with traditional medications. The approach is based on previous findings that ultrasound can influence immune cells and reduce inflammation.
Why it matters
Potential benefit: If successful, this research could provide a novel, non-invasive treatment option for patients with chronic kidney disease.
How similar studies have gone: Previous studies have shown promising results using ultrasound for immune modulation, suggesting potential success for this novel approach.
Where this research is happening
-
University of Virginia
Charlottesville, United States Active
Researchers
- Principal investigator: Goggins, Eibhlin — University of Virginia
- Study coordinator: Goggins, Eibhlin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.