Using pulmonary rehabilitation to reduce flare-ups in COPD for older adults
GEMSSTAR PERSPIRE-COPD
This study is looking at how pulmonary rehabilitation can help older adults with COPD avoid flare-ups, and it aims to find ways to improve treatments by understanding how the immune system works as we age.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10917267 on NIH RePORTER |
What this research studies
This research investigates how pulmonary rehabilitation can help prevent acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in older adults. The study aims to identify biological targets that can be modified to improve treatment outcomes, particularly focusing on the role of the immune system and age-related decline in immune function. By understanding the mechanisms behind AECOPD prevention, the research seeks to optimize pulmonary rehabilitation and pave the way for new therapeutic options. Patients participating in this research may engage in rehabilitation programs designed to enhance their lung function and overall health.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are experiencing chronic obstructive pulmonary disease.
Not a fit: Patients under the age of 65 or those without a diagnosis of COPD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments that significantly reduce hospitalizations for older adults with COPD.
How similar studies have performed: Previous research has shown promise in using pulmonary rehabilitation to improve outcomes in COPD, indicating that this approach may be effective.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Mosher, Christopher — Duke University
- Study coordinator: Mosher, Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.