Using psychoplastogens to help the injured brain recover cognitive function after trauma

Psychoplastogens to make the injured brain receptive to cognitive rehabilitation during the chronic period ofTBI

NIH-funded research Phoenix VA Health Care System · NIH-11002659

This study is looking at how special substances can help your brain heal and improve memory and thinking skills after a traumatic brain injury, making it easier for you to benefit from therapy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPhoenix VA Health Care System NIH-funded
Lab location1 site (Phoenix, United States)
Project IDNIH-11002659 on NIH RePORTER

What this research studies

This research aims to enhance the brain's ability to recover from cognitive impairments following a traumatic brain injury (TBI) by using psychoplastogens. These substances are designed to promote neuroplasticity, making the brain more receptive to cognitive rehabilitation therapies. The study will explore how these agents can be administered to improve memory and cognitive functions in individuals who have suffered from TBI. By understanding the timing and effectiveness of these interventions, the research seeks to develop new strategies for rehabilitation.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a traumatic brain injury and are facing cognitive challenges.

Not a fit: Patients who have not experienced a traumatic brain injury or those with acute injuries may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve cognitive rehabilitation outcomes for patients recovering from traumatic brain injuries.

How similar studies have performed: Previous research has shown promising results in enhancing cognitive recovery through neuroplasticity-focused interventions, suggesting potential for success in this novel approach.

Where this research is happening

Phoenix, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.