Using psychoplastogens to help the injured brain recover cognitive function after trauma
Official title: Psychoplastogens to make the injured brain receptive to cognitive rehabilitation during the chronic period ofTBI
Funded at Phoenix VA Health Care System · NIH-11002659 · Data updated 2026-11-12
This study is looking at how special substances can help your brain heal and improve memory and thinking skills after a traumatic brain injury, making it easier for you to benefit from therapy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Phoenix VA Health Care System NIH-funded |
| Lab location | 1 site (Phoenix, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| NIH project number | 5I01RX004536-02 |
| Project ID | NIH-11002659 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced a traumatic brain injury and are facing cognitive challenges.
✕Less likely to help
Patients who have not experienced a traumatic brain injury or those with acute injuries may not benefit from this research.
What this research studies
This research aims to enhance the brain's ability to recover from cognitive impairments following a traumatic brain injury (TBI) by using psychoplastogens. These substances are designed to promote neuroplasticity, making the brain more receptive to cognitive rehabilitation therapies. The study will explore how these agents can be administered to improve memory and cognitive functions in individuals who have suffered from TBI. By understanding the timing and effectiveness of these interventions, the research seeks to develop new strategies for rehabilitation.
Why it matters
Potential benefit: If successful, this research could significantly improve cognitive rehabilitation outcomes for patients recovering from traumatic brain injuries.
How similar studies have gone: Previous research has shown promising results in enhancing cognitive recovery through neuroplasticity-focused interventions, suggesting potential for success in this novel approach.
Where this research is happening
-
Phoenix VA Health Care System
Phoenix, United States Active
Researchers
- Principal investigator: Lifshitz, Jonathan — Phoenix VA Health Care System
- Study coordinator: Lifshitz, Jonathan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.